simple extractive colorimetric determination of buspirone by acid-dye complexation method in solid dosage form

Spectrophotometric determination of triclabendazole by acid-dye complexation method in bulk and pharmaceutical formulation

Two simple, accurate and sensitive spectrophotometric methods were developed for the determination of ticlabendazole in bulk and pharmaceutical formulation. These methods were based on the formation of ion-pair association complex (1:1) with bromocresol purple (BCP) and bromophenol blue (BPB). The coloured products were extracted into chloroform and measured spectrophotometrically at 420 nm. Li...

Simultaneous Determination of Metformin and Vildagliptin in Solid Dosage Form by Stability Indicating Rp-hplc Method

A simple, precise and rapid HPLC method has been developed for the simultaneous determination of Metformin and Vildagliptin in pharmaceutical dosage form. The method was carried out using Sunfire BDS C8 column (250 mm x 4.6 mm, 5 μm) and mobile phase comprised of disodium hydrogen phosphate pH 7.0±0.05 as buffer and acetonitrile in the ratio of 60:40 v/v and degassed under ultrasonication. The ...

A Rp-hplc Method for Determination of Diclofenac with Rabeprazole in Solid Dosage Form

To develop and validate simple, reproducible, stability indicating reverse phase high performance liquid chromatography for the simultaneous determination of Rebeprazole and Diclofenac in pharmaceutical solid dosage form. The method was based on HPLC separation of both drugs in reverse phase mode using Phenomenox C18 column with Waters HPLC system by using mobile phase composition of acetonitri...

Solubility enhancement of glimperide: Development of solid dispersion by solvent melt method, characterization and dosage form development

The aim of the present work was to develop immediate release dosage form of the solid dispersion of glimperide (GLIM) for potential enhancement in the bioavailability. The solid dispersions of GLIM were prepared with PEG6000, PVP K30 and Poloxamer 188, in 1:1, 1:3 and 1:5 %w/w ratio by using solvent wetting and solvent melt method. The in vitro dissolution parameters (%DE10min, %DE30min, %DE60m...

Dye Concentrations Determination in Ternary Mixture Solution by Using Colorimetric Algorithm

This publication uses a colorimetric method based on the absorbance spectra of dye solutions to improve on Beer’s law when calculating the dye concentrations of a three-component mixture. The performance of the new method is compared with that of Beer’s law evaluated at three wavelengths, and Beer’s law evaluated at 16 wavelengths. Colorimetric method gives the best prediction of d...

A new simple semimicro method for colorimetric determination of urea.